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Conference publications

Abstracts

XVII conference

Mathematical modeling of shape of human and animal life-span distributions

Krementsova A.V.

Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119334 Russia Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119334 Russia Emanuel Institute of Biochemical Physics, Russian Academy of Sciences, ul. Kosygina 4, Moscow, 119334 Russia

1 pp. (accepted)

Experimental survival curves of laboratory animal and resent 250 years life-span demographic data show that life-span distribution can considerable modified by the environmental changes. For complete estimation possible range of this modification we compare dynamics of pattern of human and animals life-span distribution in ordinary physiological conditions. The human and animal survival curves were fitted by two parameters Gompertz function. Using a negatively correlation between Gompertz function parameters that called the Strehler-Mildvan correlation we obtained 3D surfaces of survival curves characteristic vary depending on wide rage of control parameters: characteristic species life-span and cohort death rate. It have been shown that this 3D surfaces have a complex shape. In particular it have been shown nonlinear dependence between such life-span characteristic like mean life-span and variance. Obtained results open the way to understanding the role of biological and social factors in affecting to life-span distribution dynamics.



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