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Abstracts

XIX conference

The metabolism process modelling under the dot heating influence

Nechepurenko O.I., Hryhorova T.A.

Kremenchuk Mykhailo Ostrohradskyi national university, Ukraine, 39600, Kremenchuk, Pershotravneva Street, 20, +38 05366 30050, Olga.Nechepurenko@gmail.com

1 pp. (accepted)

The requirement for medical technologies and services information support has considerably increased recently. Introduction of information systems in medicine is an actual problem of a modern science. One of directions of such introduction is diagnostics and preventive maintenance of immunodeficiency. The general algorithm of the express analysis is developed and the interactive information system of the person immune condition definition express diagnostics on the basis of a thermal transfer diagnostics method is created.

As a result of work the system is recommendations about elimination of immune insufficiency by influence of temperature fields on active points of the thorax – projection of the forward median channel which is responsible for the person immune condition. For definition of optimum time of thermal influence for the concrete person there was a necessity to investigate model of a metabolism process in hypodermic area under the influence of dot heating.

The basic components of interaction described above process is the thermal radiator, a biological material (skin) as heat transmission environment and exchange vessels (capillaries) which are capacity for non-Newtonian liquids transfer with a laminar flow mode (blood) and a surface through which takes place a direct and diffusive metabolism simultaneously. Type of a radiator which is applied mainly is the infra-red radiator which time of action is out parameter of created model.

The skin is considered in model as the multilayered material which thermal characteristics change in each layer. Corium and hypodermis are important layers for modeling, because they contain a grid of exchange vessels (capillaries). The transcapillary metabolism is provided by diffusion, a filtration-absorption and micropinocytosis.

Dynamic balance on the capillary arterial and venous end is described by the Starling equation. In different texture and organs, depending on their metabolic activity, capillaries form a network of certain density – a critical thickness of a texture layer.

From the mathematical point of view, for development of mathematical model which would consider specificity of all interaction basic components described above process, it is necessary to unite elements of geodynamics and heat transmission problems. The dynamic balance on the ends of capillaries is an indispensable condition for definition of optimum time of heating.



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